Computational superpowers

Computational biology will never cease to amaze me. I wanted to check how my protein of interest, an esterase that has evolved from a hemolymph-based hormone processing enzyme important in insect development, is managing to survive in the harsh environment of trophallactic fluid (ph 2!). There are some amazing tools out there! First I used I-TASSER to map my protein's sequence onto those of proteins whose structure is known, then evaluate which is the best match. Then I can take that information and feed it into PropKa to figure out the state of charge on each molecule of the protein in a given pH environment. Then! I can pop all of this into Chimera and visualize the charge all around the protein, and even head over to CASTp to look into the binding pocket! All of these magical science powers are available on the internet for free for non-profit/research use. 

 My beauty. The serine in the active site is highlighted. 

My beauty. The serine in the active site is highlighted. 

Adria LeBoeufscience, geekery
Djerassi Science-Art Residency

This experience has been amazing. The phenomenal fellow residents here (ranging from biochemistry professor to game designer with most people holding multiple titles/identities) have been constant inspiration, not only in their science and/or art, but in the way that each has built a way to have both in his or her life. This is a constant struggle in a world where we are constantly being told we need to focus exclusively on one or the other. It's wonderful to be here and to clearly and unabashedly be a person doing both.  

One of my biggest lessons here has been that I should quit stressing about doing both and just do them. There have been a number of jokes about one positive of ageing: that you care less and less about pleasing others or fitting what the world wants from you. Working on it. 

Another wonderful surprise has been the future-focused discussions/projects. A lot of the residents are working on projects about our shared future and how we are arriving in it, how the future is a participatory creation. 

What have I been doing? I've been working on a new play tentatively called Unsupervised Learning about science, hubris and the wild confidence necessary for innovation. More info to come.  

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Adria LeBoeuf
Visit with University of Geneva

I had the pleasure of visiting the Department of Biochemistry at the University of Geneva last week. I was giving a talk as part of a symposium featuring six other women scientists and one man, all doing fascinating work on different aspects of biology involving distributed processes, cellular forces and membrane trafficking. Needless to say, it was a great visit. It's a very creative department tackling diverse problems and creating very cool new chemical biology tools. I hope to get the opportunity to interact more with them in the future!

Adria LeBoeuf
Institute of Evolution in Haifa

Yesterday I had the pleasure of visiting Haifa, the Privman lab, and the Institute of Evolution at the University of Haifa to give a seminar about my work social fluids and to work on the neofunctionalized enzyme collaboration. What a beautiful spot! And they said it wasn't a clear day....

Adria LeBoeuf
OMA Visiting Fellowship

Great news: Thanks to my cool ongoing project with the Dessimoz group at UNIL and the Privman group in Haifa on social neofunctionalization of hormone processing enzymes I get to travel a few times back to Lausanne for scientific purposes through an OMA visiting fellowship! Why? We're using the excellent and multi-faceted OMA to look at this neofunctionalization.

Adria LeBoeuf
Arrival at the Weizmann

Big change! At the start of March I moved to the Weizmann Institute of Science to work for most of this year in Ofer Feinerman's lab with their awesome trophallaxis tracking system in the Department of Physics of Complex Systems.

It's exciting to plant some roots in a new place, especially a new place with great weather and great hummus!

 Fluorescent ants and larvae! WOW. 

Fluorescent ants and larvae! WOW. 

Adria LeBoeuf
University of Konstanz and University of Zurich!

I'm getting the double pleasure of getting to talk about my work on two campuses on the very same day: Feb 22, 2017. In Konstanz I will be talking with folks in the neurobiology side of things (social fluids are a type of chemical communication), while in Zurich I'll be talking more with evolutionary biologists and focusing more on the evolution of parental care. Thank you to Christoph Kleineidam (Konstanz) and to Barbara König (Zurich) for welcoming me!

Adria LeBoeuf
HEC Lausanne course begins!

Last year I had the pleasure of debuting a new six-week course for doctoral students in the Faculty of Business and Economics in at the University of Lausanne on "Mastering the Art of Public Speaking." It was a wild ride that ended in a beautiful event in La Grange de Dorigny and 6 excellent talks. 

This year we are doing the course again but in just three days spaced out over a week! It starts next week. I can't wait to meet this year's class! The final event will be February 28th at 2pm, Extranef room 125, at the University of Lausanne. 

A nice article on the course.

Adria LeBoeuf
Lots of press about my eLife paper! (Science, Nature, WIRED...!)

An ant’s kiss may hide a sneaky form of communication

 

Science, Nov 29, 2016 "An ant’s kiss may hide a sneaky form of communication"

WIRED, Nov 29, 2016 "Carpenter ants 'throw up' on each other to say hello"

Gizmodo, Nov 29, 2016 "Ants Exchange Messages When They Make Out"

Science Daily, Nov 29, 2016 "Ants communicate by mouth-to-mouth fluid exchange"

DailyMail, Nov 29, 2016

Eurekalert, Nov 29, 2016

Phys.org, Nov 29, 2016

Business Standard, Nov 29, 2016

UPI, Nov 29, 2016

NewAltas, Nov 29, 2016 "When ants kiss, it's all about the chemistry"

La Vanguardia, Nov 30, 2016 "Las hormigas también se besan, y los científicos empiezan a entender el porqué"

Live Science, Nov 30, 2016 "For Ants, a Kiss Is Not Just a Kiss…It's Communication"

Mental Floss, Dec 2, 2016 "Ants Communicate by Swapping Spit"

Der Standard, Dec 4, 2016 "Soziale Insekten kommunizieren, indem sie Flüssigkeit austauschen"

STEAM register, Nov 29, 2016

Science Explorer, Nov 29, 2016

Sky.it, Nov 30, 2016

LaInformacion, Nov 30, 2016

India.com, Dec 1, 2016

New Zealand Herald, Dec 3, 2016

Yahoo Japan, Dec 13, 2016

EntomologyToday, Dec 7, 2016

Nature, Dec 15, 2016 "Ants 'talk' by swapping spit"

Boston Globe Jan 9th, 2017

Krone Jan 9th, 2017

Die Presse, Jan 9th, 2017

NZZ, Jan 9th, 2017

La Liberté, Jan 10th, 2017

Adria LeBoeuf
Column in Crastina!

Check out the column I wrote for the Science Communication organization Crastina

GREAT PRESENTATION ≠ BAD SCIENCE

How come researchers who are great presenters often are disregarded as bad scientists? Adria LeBoeuf, multi-disciplinary scientist and communications evangelist, thinks there has to be an end to the social punishment of clear and passionate oral communication.

 

Adria LeBoeuf
Visit to IST, Vienna

Honored to be invited to go visit the IST Austria thanks to Sylvia Cremer in early December. I'll be talking at their Evolunch seminar series. Sylvia's lab focused on social immunity in ants, looking at how their communities can prevent epidemics. 

Adria LeBoeufseminar
Visit to Cambridge

Had a great visit to the Zoology Department at Cambridge at the end of October for their Behaviour, Ecology, Evolution Seminar series. I was hosted by the fantastic Hannah Rowland. While I meet a bunch of folks doing fascinating work, it was super exciting to meet Becky Kilner and the people in her lab working on Burying Beetles. These beetles engage in serious parental care (both parents!), where they feed their young through trophallaxis!  

Adria LeBoeufseminar